The article considers the theoretical and methodological bases of management of regional development on the basis of the spatial organization of economy of the municipality. The institutional framework of the management of the territory has been researched, the main purpose of management of social — economic development of a municipality is establishment of the socially oriented economy at the level of municipal education has been specified. The existing problems associated with the creation of programs of social-economic development of the municipality have been described. The author reasons the necessity to define the directions of spatial development of the territory as a methodological basis for effective management through a comprehensive analysis of the socioeconomic situation of the municipality. Spatial development actualizes the establishment of methods to manage socio-economic development of municipal formations in the region to overcome intraregional asymmetry and to plan the development of the economy of the municipality by economic activity.