The article is devoted to the philosophical problem “Negative Methodology” which has not been sufficiently studied before. The Negative Methodology is developed by the author in the past as part of the cognitive forms of social consciousness. The attention in this article is given to the lack of a theoretical analysis of the negative features of the methodology in the field of morality. The article examines the most general aims of the negative methodology in the field of morality. The author reveals the practical importance of negative methodology in the sphere of negative morality. The author analyzes the six principles of the negative methodology in the field of morality which illustrates his logic.(You should not be conceited. You should not reject your predecessors’ achievement. You should not limit yourself by your own opinion. You should not try to please everyone. You should not break the measure. You should not rely only on the authority of moral activity.) The author’s arguments are based on extensive examples from the field of philosophy of science, history, physics and art. The paper represents a comparison of the negative moral guidance to both positive and negative regulations of religion. This knowledge may be useful for university teachers, undergraduates and postgraduate students, as well as all for those who are interested in the problems of morality and philosophy.