The data on investigation of lipid profile peculiarities in different sex and age groups of men and women are given. Measures of lipid profile: level of total cholesterol, low density lipoprotein cholesterol, high density lipoprotein cholesterol, triglycerides and atherogenic index in different age groups of men and women in Barnaul have been analyzed. It is shown that the levels of total cholesterol and low density lipoprotein cholesterol of examined people are over the limit. In women group these indices were significantly higher than in men. Levels of high density lipoprotein cholesterol and triglyceride in both of sex groups were normal. With the age, the levels of total cholesterol and low density lipoprotein cholesterol in serum increases, correspondingly increases the atherogenic index. The content of triglycerides is not changing significantly but the level of high density lipoprotein cholesterol tends to decrease. The biochemical analysis of blood was used for the classification of lipid violations spectrum. It is presented that among lipid disorders of women and men hypercholesterolemia was recorded most often. On the second place in men group — hypo- α-cholesterolemia, and in women group — hypertriglyceridemia were registered.