Methodology for calculating efficiency of created dedusting systems is presented. This work is devoted to evaluation of various logical models and operation principles of new devices for the analysis of dust-like materials. Proposed devices can significantly an analysis duration in comparison with other well-known methods. The proposed dedusting systems are based on centrifugal inertia systems with an air exhaust louver, wet and magnetic systems. It is demonstrated that equation of parameters relationship properly developed for a new device leads to non-zero estimation errors. Thus, problems of size evaluation for particles and fractions, problems of control and diagnostics can be solved within a framework that goes beyond traditional approach. The efficiency of the proposed technique in different experimental conditions is evaluated and proved to fall into compliance with regulations on residual dust concentration with consideration of dust collector operational reliability.