In the paper, features of deformation and destruction of a multilayer-coated material under high-velocity impact interaction are investigated. Three-dimensional boundary problem is solved numerically by the finite element method with explicitly defined multilayer coating. The Prandtl-Reuss equation and the Mi-Gruneisen equation of state are utilized for mechanical reaction modeling of a steel backplate, a projectile and a covering sublayer made of NiAl. An elastic-brittle model describes the behavior of covering material made of WC–Co. Fracturing description of the material with high strength coating is provided by Hoffman criterion that considers various strength of stretching and compression. Influence of high strength coating on evolution of wave pattern and stress-strain state of a steel backplate is examined. It is shown that multilayer coating increases dynamic strength of a steel base. Also, it is found that reduction of projectile penetration power by multilayer coating depends nonlinearly on speed of interaction.