The article determines the peculiarities of settling of North and Central Mongolia in the light of the possible reaction on the conditions of the changing environment at the turn of MIS –3 and MIS-2. To state the continuity and the reasons for the possible gaps in the continuous cultural development of human populations, the analysis of chronostratigrafical allocations of industrial ensembles was conducted. The analysis is based on complete data of all published radiometric definitions for Pleistocene monuments in Mongolia. Considering the dates allocations, the periodicity of settling and their correlation with the main climatic characteristic of the second half of Late Pleistocene are singled out. The peak indicators in the settling episodes correlate with the main gaps in the cultural development in the Paleolithic of Mongolia. If there might be a cultural continuity for the changing traditions of the Early Upper Paleolithic and the Beginning of Upper Paleolithic in Mongolia, to trace the cultural continuity at the next stages is rather difficult. We cannot exclude the possibility of depopulation of the territory of Mongolia in the period of the maximum of the Sartan glaciations.