The results of the main fault zone geomorphological study of the largest earthquakes in the Khangai Mountains in 1905 revealed significant transformation in the topography of this region caused both by the seismic event and its after-effects. The methodological basis of the research was to decode the digital satellite imagery materials held on Google’s system. It is established that there exists zonal sequence which is associated with the main series of mountain ridge system faults, the appearance of the ribbed forms of watershed and mountain slope exposures, changes of the patterns and the structure of the erosion valleys. The article contains preliminary estimation of the scope of geomorphological changes which happened during the last 100 years in the area about 1400 square kilometers that approximately corresponds to 10–15% of the Russian Altai system territory. That is consistent with the author’s ideas of a heterogeneous and multidirectional nature of the combined mountain systems development, conjoined with the relative permanence of the mountain building processes.