English Russian
Izvestiya of Altai State
University Journal
The News of Altai State University

 Архив журнала «Известия АлтГУ», начиная с 2017 г., размещен на новой версии сайта http://izvestiya.asu.ru
 Актуальная информация о журнале размещена на новой версии сайта http://izvestiya.asu.ru

Print ISSN 1561-9443
On-line ISSN 1561-9451
Issues list
Table of Contents
Physical science
About the Journal
Editorial board and Editorial advisory board
Regulations on reviewing research papers
Rules of the articles representation
Publication Ethics of the journal «Izvestiya of Altai State University»

A.A. Shaidurov, A.S. Bublikov

Development of a Cancer Diseases Classification Model Using Artificial Intelligence

The paper deals with the possibility analysis of developing a cancer diseases classification model based on layered artificial neural networks. We studied the data obtained by the IMMUNOSIGNATURE technology. Immunosignaturing requires a drop of test subject blood that contains cells of immune system to be applied to a biochip. The biochip is divided into sectors with unique amino acid sequences. Depending on the intensity of the immune response manifestation in specific cells, a specific profile (signature) is formed for a certain individual. The complexity of immunosignature data analysis lies in external stochastic influence on the obtained results. In the paper, aspects of correlation analysis data correction to get rid of random artifacts are considered. Data normalization procedure to minimize the impact of systemic distortions due to the influence of external factors, such as temperature, humidity, substance concentration, etc., is discussed. Classification is performed by the backpropagation artificial neural network.

DOI 10.14258/izvasu(2015)1.2-32

Key words: artificial neural network, a method of confidence intervals, correlation analysis, technology IMMUNOSIGNATURE, oncology, breast cancer

Full text at PDF, 747Kb. Language: Russian.

Altai State University (Barnaul, Russia)
E-mail: shaidurov@phys.asu.ru

Altai State University (Barnaul, Russia)
E-mail: madsilver@rambler.ru


Print Edition of "Izvestiya of Altai State University" © 1996-2017 Altai State University.
All rights reserved. Any of parts of a journal or edition as a whole cannot be reprinted without the written sanction of the authors or publisher. On purchase of a journal to address to ASU publishing house:
Altai State University. 656049, 66 Dimitrova street, Barnaul, Russia. Telephone + 7 (3852) 366351.