The purpose persisting article is an attempt in process of the study mechanism regulations territorial inequality to use the notions to sociologies, expecting not mechanics carrying notion from one science in another, but their creative interpretation.

The key determination of study is a notion "social-territorial development of the region", under which is in this instance understood changes to territorial organization of vital activity of the population, conditioned shift in demographic, economic and social-home sphere of the region.

Hypothetical we in its study come from suggestion that reaction of regional social-economic systems on change national macroeconomics parameter is defined in main particularity social-territorial structure of the region. Consequently, accepted in study approach to analysis social-territorial development of the region allows to approach to decision of the problems its firm development, lead the scientific base under development of its prospects.