Conducted measurement microhurdness for urinary stones with the different composition and structure. Discovered essential influence of construction urolithes on its local mechanical features. In the event of urinary stones with the spherical symmetrical structure revealed circle changes microhurdness when turning from one layer to other. For rest stones with the radial symmetry was observed anisotropy microhurdness. Tinned data be of interest an urolithes for the forecasting of particularities of destroying.